Prevalence of mef(A) and erm(B) in macrolide-resistant Streptococcus pneumoniaeisolates in children with pneumonia in Nghe An (2019-2021)

The present study aimed to determine the incidence of erm(B) and mef(A) among macrolide-resistant S. pneumoniae isolated in children with pneumonia Nghe An province (2019-2021). A total 126 clinical pnemococcal strains from unvaccinated less than 5 years age at Obstetrics Pediatrics Hospital, Vietnam during period Nov 2019 Dec 2021. All were identified using conventional microbiological method, VITEK® 2 Compact system specific PCR. antimicrobial resistance patterns determined system. Polymerase chain reaction (PCR) assay used detect macrolide genes mef(A). Of isolates, 92.1% (116 126) PCR positive for 57.9% (73 120 (95.3%) had and/or gene 54.8% both positive. findings current showed high prevalence isolates province.